THE QUARTER NOTE
3RD QTR 2016 - FORMALDEHYDE AND YOU
Formaldehyde is ubiquitous. If you are allergic to it, it will cause you to suffer asthma-like pulmonary function deficits that will not only be triggered by formaldehyde itself, but also by other aldehydes commonly found in perfumes and other odorants. It also is capable of causing allergic reactions on skin in sensitized individuals. Formaldehyde is typically present in most homes from numerous sources including particle board which may be used in various cabinets, flooring, urea-formaldehyde insulation, tobacco smoke, fumes from gas stoves, cooking processes, and various consumer products including cosmetics and crease-resistant new clothing. Particle board is made up of wood chips held together with a phenol-formaldehyde resin which can off-gas formaldehyde. If you think that you are allergic to formaldehyde, you can go to your allergist and be patch tested; but this test is only meaningful if the results are positive. A negative test does not mean that you are not allergic to formaldehyde. Patch tests for formaldehyde have been shown to be unreliable in many cases. Formaldehyde is also a known animal carcinogen producing nasal tumors in rats, and a suspect human carcinogen linked to lymphatic and hematopoietic cancers including lymphoma, multiple myeloma, and leukemia; but the association is not strong. Formaldehyde also has been shown to result in mutagenicity and to produce chromosomal aberrations.
1ST QTR 2016 - LEAD IN DRINKING WATER, Flint Michigan
The contamination of drinking water in Flint, Michigan, is a disaster of massive proportions. Considering the fact that children have been exposed from the time that they were conceived in the womb to their birth and development represents a template for numerous neurological and developmental problems. Exposure from drinking water consumed by the mother while the child is still in the womb coupled with direct exposure of the neonate via drinking water and foods cooked in contaminated water results in exposure during the most critical period of a child's development.
The first three years of life is a period of incredible growth in the neonate. By age 3, the brain has grown dramatically producing billions of cells and hundreds of trillions of connections, or synapses, between these cells. Many of these developmental processes can be altered by the presence of lead in brain tissue.
Thus, children are the most susceptible to the toxic effects of lead. Lead is passed from mother to fetus and neonate via transplacental transfer and mother's milk. From fetus to neonate to young child, lead is accumulated faster in children than in adults, resulting in serious neurobehavioral problems, delayed developmental effects, and mental retardation. Lead is distributed to the brain, liver, kidney, and bones. Lead also disrupts hemoglobin formation causing anemia. Currently, no safe level of lead in a child's blood has been identified, but a level of 5 µ/dl is considered a good guideline for maximum lead levels in children; however, there are scientific studies showing adverse effects at blood levels of less than 5 µ/dl. In assessing the potential causal relationship in lead cases, we must be certain of the source. In the case of contaminated drinking water in Flint, Michigan, there is no question of the source.
National Institutes of Health Update:
For additional information see a March 2002 Centers for Disease Control and Prevention publication entitled "Managing Elevated Blood Lead Levels Among Young Children" [http://www.cdc.gov/nceh/lead/casemanagement/managingEBLLs.pdf] and www.consultox.com.
3RD QTR 2015 - THE ANIMAS RIVER IN COLORADO, NEW MEXICO, AND UTAH IS DEAD
The Animas River Is Dead - Heavy Metals
The Animas River is Dead - Health Effects
The Animas River is Dead - No Practical Solution
The Animas River is Dead - Heavy Metal Mobility
The Animas River is Dead - Misconceptions
2ND QTR 2015 - TESTIMONY IN HONG KONG
Recently, I returned from a two-week business trip in Hong Kong. During that time, I provided five days of court testimony for the defense of a shampoo product containing trace amounts of 1,4-dioxane. What qualifies me to testify on such a topic? I am a board certified consulting toxicologist and a recognized expert witness in the field of toxicology. I have over 30 years of experience as a consultant in toxicology providing expert testimony in toxicology for both plaintiff and defense. In preparation for this case, I expended over 100 hours studying the issue of 1,4-dioxane in shampoo and other consumer products. Further, I have personally used 1,4-dioxane regularly as a solvent while doing research in the field of synthetic organic chemistry for over 10 years.
I became involved in this matter because a libel suit was brought against a magazine who claimed that the use of a particular shampoo would increase the risk of cancer. 1,4-dioxane has been shown to produce cancer in animals treated at doses that are 40,000 times or more greater than the doses that man would encounter in using shampoo. Animal studies showed an increase in cancer incidences that most probably resulted from cytotoxicity followed by cell proliferation and endogenous mutations leaving the tissue subject to promotion by 1,4-dioxane or other factors. A key piece of information is that 1,4-dioxane is not genotoxic. This fact makes it clear that there is a threshold for liver cancer in animal studies which has been demonstrated repeatedly. There is also a threshold in man, and I can clearly state, as others have, that there is no risk of cancer in man as a result of using shampoo containing as much as 30 ppm, or more. Similarly, other consumer products containing 30 ppm of 1,4-dioxane are safe to use without an increased risk of cancer.
©2010-2015 Constultox Limited Damariscotta, Maine. Website Maintained by Gudroe Technology Group